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	Provedor de dados BJMBR (1) Autor Ciancaglini,P. (1) Millán,J.L. (1) Simão,A.M.S. (1) Yadav,M.C. (1) Palavra-chave ATP (1) Alkaline phosphatase (1) Biomineralization (1) Calcification (1) Lipids (1) Pyrophosphate (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Ano 2010 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Proteoliposomes as matrix vesicles' biomimetics to study the initiation of skeletal mineralization BJMBR Simão,A.M.S.; Yadav,M.C.; Ciancaglini,P.; Millán,J.L.. During the process of endochondral bone formation, chondrocytes and osteoblasts mineralize their extracellular matrix by promoting the formation of hydroxyapatite (HA) seed crystals in the sheltered interior of membrane-limited matrix vesicles (MVs). Ion transporters control the availability of phosphate and calcium needed for HA deposition. The lipidic microenvironment in which MV-associated enzymes and transporters function plays a crucial physiological role and must be taken into account when attempting to elucidate their interplay during the initiation of biomineralization. In this short mini-review, we discuss the potential use of proteoliposome systems as chondrocyte- and osteoblast-derived MVs biomimetics, as a means of reconstituting a phospholipid... Tipo: Info:eu-repo/semantics/article Palavras-chave: Alkaline phosphatase; Biomineralization; Calcification; Lipids; Pyrophosphate; ATP. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000300003 Registros recuperados: 1 Primeira ... 1 ... Última

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